Adcimab 100mg Injection

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16ml Injection in 1 Vial Out of Stock
₹ 21000
16ml INJECTION 1 Vial ₹ 21000
  • Out of Stock

Adcimab 100mg Injection

16ml Injection in 1 Vial
₹ 21000
16ml INJECTION | 1 Vial
₹ 21000
0 people have bought this recently

Adcimab 100mg Injection Information

Adcimab is a monoclonal antibody used in the treatment of various cancers. It works by inhibiting angiogenesis, the process by which tumors develop new blood vessels to sustain their growth. Adcimab specifically binds to vascular endothelial growth factor (VEGF), a protein that promotes the formation of new blood vessels. By neutralizing VEGF, Adcimab starves tumors of their blood supply, inhibiting growth and progression. 

Indications:

  • Colorectal Cancer: Advanced or metastatic stages, often in combination with chemotherapy.
  • Non-Small Cell Lung Cancer (NSCLC): Metastatic cases, in combination with chemotherapy.
  • Renal Cell Carcinoma (RCC): Advanced stages, often combined with interferon alfa.
  • Cervical Cancer: Persistent, recurrent, or metastatic cases.
  • Glioblastoma: As a second-line treatment.
  • Ovarian Cancer: Platinum-resistant and recurrent forms.

Adcimab is a cornerstone in targeted cancer therapy due to its innovative approach to halting tumor growth. However, its use requires careful consideration of patient-specific factors and potential side effects. Collaborating with oncologists and monitoring during treatment ensures the best outcomes for patients.

Dosage and Administration:

  • Formulation: Adcimab is available as an intravenous infusion.
  • Typical Dosing: Colorectal Cancer: 5-10 mg/kg every 2 weeks.
  • NSCLC: 15 mg/kg every 3 weeks.
  • Dosage varies based on the cancer type, patient condition, and combination regimen.

Side Effects: Hypertension (high blood pressure), Fatigue, Nausea and vomiting, Nosebleeds, Proteinuria (protein in the urine), 

Severe side effects: Gastrointestinal perforations, Hemorrhage, Arterial thromboembolism, Nephrotic syndrome.

Contraindications

  • Hypersensitivity to Adcimab or its components
  • Active infections or significant recent surgical procedures
  • Uncontrolled hypertension

Precautions

  • Pregnancy and Lactation: Adcimab may harm the fetus; effective contraception is advised during and after treatment.
  • Wound Healing: Therapy should be delayed in patients undergoing major surgery.
  • Monitoring: Regular monitoring of blood pressure, kidney function, and signs of bleeding is essential.

Storage and Handling

  • Store Adcimab vials at 2°C to 8°C (36°F to 46°F).
  • Do not freeze or shake the vials.
  • Use the prepared solution immediately or within the recommended timeframe.

 



Adcimab 100mg Injection Benefits & Uses

Adcimab 100mg Injection is used to treat the following -

Main Benefits

Other Benefits

Adcimab 100mg Injection Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Kidney Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Adult(Female)
  • Disease: Ovarian Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Kidney Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor

Adcimab 100mg Injection Related Warnings

  • Is the use of Adcimab 100mg Injection safe for pregnant women?


    Pregnant women may get severe side effects after taking Adcimab. If you are pregnant, do not take Adcimab without a doctor's advice.

    Severe
  • Is the use of Adcimab 100mg Injection safe during breastfeeding?


    Women who are breastfeeding may experience severe harmful effects after taking Adcimab. It should only be taken after medical advice.

    Severe
  • What is the effect of Adcimab 100mg Injection on the Kidneys?


    There may be some adverse effects on kidney after taking Adcimab. If you observe any such side effects, stop taking this drug. Consume this medicine again only if your doctor advises you to do so.

    Moderate
  • What is the effect of Adcimab 100mg Injection on the Liver?


    Adcimab can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Adcimab 100mg Injection on the Heart?


    Adcimab can have moderate side effects on the heart. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate


Severe Interaction of Adcimab 100mg Injection with Other Drugs

Adcimab 100mg Injection should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Adcimab 100mg Injection Contraindications

If you are suffering from any of the following diseases, you should not take Adcimab 100mg Injection unless your doctor advises you to do so -



Frequently asked Questions about Adcimab 100mg Injection

  • Is this Adcimab 100mg Injection habit forming or addictive?


    Adcimab 100mg Injection is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Adcimab 100mg Injection you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Adcimab 100mg Injection should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Adcimab 100mg Injection is unable to treat or cure mental disorders.

    No

Adcimab 100mg Injection Interactions with Food and Alcohol

  • Interaction between Food and Adcimab 100mg Injection


    Taking Adcimab 100mg Injection with food is safe.

    Safe
  • Interaction between Alcohol and Adcimab 100mg Injection


    No research has been done on this till date. Therefore, it is not known what the effect of taking Adcimab 100mg Injection with alcohol will be.

    Unknown


See all substitutes for Adcimab



This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience



References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 224-225

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 871

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Avastin® (bevacizumab)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Avastin® (bevacizumab)



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16ml Injection in 1 Vial