DHEA for Anti-Aging, Fertility, and More: Is It Safe?

Although it is advisable to take DHEA supplements for health, there is still a lack of research in this regard. Therefore, it is difficult to clearly state how beneficial it is to take DHEA supplements. Let us know in detail about the benefits of Dehydroepiandrosterone based on the available research and information -

Short-term and controlled use of DHEA is generally considered safe. Studies suggest that taking up to 50 mg of DHEA daily for up to two years is safe. However, excessive intake may lead to side effects like acne and stomach pain.

Other research indicates that taking 50-100 mg of DHEA daily for a short period may not be harmful. However, long-term use at higher doses may increase the risk of hormone-related cancers, such as prostate, breast, and ovarian cancer, due to its steroid-like effects on the body.

(Read more – Androgen hormones)

While DHEA offers some health benefits, its prolonged use can have serious drawbacks. Here are some potential risks and precautions:

Increased Risk of Bleeding: DHEA can slow down blood clotting, raising the risk of excessive bleeding. Taking it alongside foods like garlic, ginger, ginkgo, and Panax ginseng may further increase this risk.

Hormonal Imbalances: DHEA can cause oily skin, acne, and excessive hair growth in women (hirsutism).

Mental Health Concerns: This supplement may worsen symptoms of mental disorders.

Impact on Diabetes: DHEA can interfere with insulin function, making it unsuitable for diabetic patients. Those taking DHEA should monitor their blood sugar levels closely.

Not Recommended for Mood Disorders: Individuals with mood-related conditions should avoid DHEA.

Worsening of PCOS Symptoms: Women with polycystic ovary syndrome (PCOS) may experience worsening symptoms with DHEA intake.

Liver Health Risks: Long-term use may negatively affect liver function.

Not Safe for Pregnant or Breastfeeding Women: Women who are pregnant or nursing should avoid DHEA.

Effect on Cholesterol Levels: DHEA may reduce levels of high-density lipoprotein (HDL or "good" cholesterol).

Increased Cancer Risk: Long-term use can elevate the risk of hormone-sensitive cancers, including breast, ovarian, and prostate cancer.

Heart Disease Concerns: Individuals with high cholesterol or heart conditions should avoid DHEA due to its potential impact on blood circulation.

(Read more – Hormone replacement therapy for menopause)

DHEA hormone plays a very important role in the body due to its many functions. Its benefits include reducing aging, relief from fertility problems, improving libido, but taking its supplements without consulting a doctor and in excessive amounts can also cause many side effects. Therefore, consume and use DHEA topical only on proper advice.