Virafin (Interferon Alpha 2B) is an antiviral and immunomodulatory medication. It belongs to the class of interferons, proteins produced by the body in response to viral infections, and is used in the treatment of various viral and oncological conditions.

Uses:

• Treatment of chronic Hepatitis B and C.

• Management of certain types of cancer, including malignant melanoma and hairy cell leukemia.

• As part of combination therapy for COVID-19-related complications.

Mechanism of Action:
Interferon Alpha 2B enhances the immune response by activating natural killer cells and macrophages, increasing the expression of major histocompatibility complex (MHC) antigens, and inducing other antiviral proteins.

Onset of Action:

• The onset of action varies depending on the condition being treated, typically showing effects within a few days to a week.

Duration of Action:

• The duration of therapeutic action may extend over several weeks, requiring continuous monitoring.

Dosage:

• The dosage of Virafin depends on the disease being treated.

• For Hepatitis B and C: Administered as an injection under the skin or into a muscle, typically 3 million IU thrice weekly.

• For COVID-19: A single dose of subcutaneous injection (dose as per physician's prescription).

Side Effects:
Common side effects may include:

• Flu-like symptoms (fever, chills, muscle aches)

• Fatigue and headache

• Nausea and vomiting

• Hair thinning

• Mood changes and depression (in some cases)

Precautions:

• Avoid use in patients with severe liver or kidney impairment.

• Use with caution in patients with psychiatric disorders.

• Regular blood tests are recommended to monitor blood cell counts and liver function.

Contraindications:

• Hypersensitivity to interferon or any component of the formulation.

• Autoimmune hepatitis or decompensated liver disease.

Storage Instructions:

• Store at 2°C to 8°C (refrigerated). Do not freeze.

• Protect from light and keep out of reach of children.