Protamine Sulphate Information

Protamine Sulphate is a commercial drug that is prescribed in the form of Injection. Drug Overdose are some of its major therapeutic uses.

The correct dosage of Protamine Sulphate depends on the patient's age, gender, and medical history. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Detailed information has been provided in the dosage section.

Besides the aforementioned side effects, there are other adverse effects of Protamine Sulphate as well, which are listed below. Usually, these side effects of Protamine Sulphate go away soon, and do not persist beyond the duration of the treatment. Please speak with your doctor if these side effects worsen or persist for a longer duration.

Protamine Sulphate's effect during pregnancy is Moderate and Unknown while nursing. Further, the section on Protamine Sulphate related warnings talks about Protamine Sulphate's effects on the liver, heart and kidney.

Protamine Sulphate is contraindicated in people with pre-existing medical conditions like Heart Disease as it can result in adverse effects. The section on Protamine Sulphate contraindications lists all such conditions.

Drug interactions for Protamine Sulphate have been reported in the medical literature. See below for a complete list.

You should also be aware that Protamine Sulphate is not safe while driving, and is not addiction.

Protamine Sulphate Benefits & Uses
Protamine Sulphate Dosage & How to Take
Protamine Sulphate Side Effects
Protamine Sulphate Related Warnings
Severe Interaction of Protamine Sulphate with Other Drugs
Protamine Sulphate Contraindications
Frequently asked Questions about Protamine Sulphate
Protamine Sulphate Interactions with Food and Alcohol

Protamine Sulphate Benefits & Uses

Protamine Sulphate is used to treat the following -

Other Benefits

Protamine Sulphate Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Drug Overdose Before or After Meal: As advised by a physician Single Maximum Dose: 1 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: used in severe heparin overdose
Geriatric	Disease: Drug Overdose Before or After Meal: As advised by a physician Single Maximum Dose: 1 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: used in severe heparin overdose
13 - 18 years (Adolescent)	Disease: Drug Overdose Before or After Meal: As advised by a physician Single Maximum Dose: 1 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: used in severe heparin overdose
2 - 12 years (Child)	Disease: Drug Overdose Before or After Meal: As advised by a physician Single Maximum Dose: 1 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: used in severe heparin overdose

Protamine Sulphate Related Warnings

Is the use of Protamine Sulphate safe for pregnant women?

Pregnant women may experience moderate side effects from Protamine Sulphate. It is best to stop taking Protamine Sulphate immediately and inform your doctor if you notice any discomfort.

Moderate
Is the use of Protamine Sulphate safe during breastfeeding?

No research work has been carried out till date on effect of Protamine Sulphate on breastfeeding women. So it is not known whether taking Protamine Sulphate will cause side effects or not.

Unknown
What is the effect of Protamine Sulphate on the Kidneys?

Protamine Sulphate is not harmful for kidneys.

Safe
What is the effect of Protamine Sulphate on the Liver?

There are no any side effects of Protamine Sulphate on the liver.

Safe
What is the effect of Protamine Sulphate on the Heart?

Very few cases of side effects of Protamine Sulphate on the heart have been reported.

Mild

Severe Interaction of Protamine Sulphate with Other Drugs

Protamine Sulphate should not be taken with following medicines due to severe side effects it may cause to patients -

Life Threatening

Mifepristone

Severe

Abciximab

Allopurinol

Argatroban

Argatroban Injection

Azithromycin

Bemiparin

Protamine Sulphate Contraindications

If you are suffering from any of the following diseases, you should not take Protamine Sulphate unless your doctor advises you to do so -

Heart Disease
Edema

Frequently asked Questions about Protamine Sulphate

Is this Protamine Sulphate habit forming or addictive?

Protamine Sulphate does not cause addiction.

No
Is it safe to drive or operate heavy machinery when consuming?

No, you should do not do anything that requires concentration and attention as the Protamine Sulphate can make you feel drowsy.

Dangerous
Is it safe?

Protamine Sulphate is safe but it is important to consult a doctor before taking it.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

There is no benefit of taking Protamine Sulphate for mental disorders.

No

Protamine Sulphate Interactions with Food and Alcohol

Interaction between Food and Protamine Sulphate

Information is not available on the interaction of any foods with Protamine Sulphate, due to a lack of research on this.

Unknown
Interaction between Alcohol and Protamine Sulphate

Due to lack of research, nothing can be said about side effects of consuming alcohol while taking Protamine Sulphate.

Unknown

See all substitutes for Protamine Sulphate

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

Protamine Sulphate Injection