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Azadine is an antineoplastic agent that works as a hypomethylating agent. It is primarily used in the treatment of certain types of myelodysplastic syndromes (MDS), a group of bone marrow disorders. Azadine helps restore normal gene function, promoting healthy blood cell production and inhibiting the growth of abnormal cells in the bone marrow.
Azadine incorporates into DNA and RNA, inhibiting DNA methyltransferase. This results in hypomethylation of DNA and reactivation of silenced tumor suppressor genes. The drug also disrupts RNA processing, which may contribute to its anti-cancer effects. These mechanisms slow or stop the growth of abnormal cells and promote normal cell development.
Common Side Effects: Nausea and vomiting, Fatigue, Anemia, thrombocytopenia, and neutropenia, Injection site reactions (e.g., redness, pain), Diarrhea or constipation.
Serious Side Effects:
Monitoring Requirements:
Standard Dose:
Administration Tips:
Azadine 150mg Injection is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
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Geriatric |
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Based on research, the following side effects have been observed when Azadine 150mg Injection is used -
Severe
Moderate
Mild
Common
Is the use of Azadine 150mg Injection safe for pregnant women?
Azadine has many dangerous side effects in pregnant women. If you are pregnant, do not consume Azadine without medical advice.
Is the use of Azadine 150mg Injection safe during breastfeeding?
Taking Azadine may lead to serious side effects if you are breastfeeding. Azadine should not be taken by breastfeeding women unless prescribed by the doctor.
What is the effect of Azadine 150mg Injection on the Kidneys?
Azadine rarely affects the kidneys.
What is the effect of Azadine 150mg Injection on the Liver?
Azadine may have mild side effects on the liver. Most people will never see any effect on the liver.
What is the effect of Azadine 150mg Injection on the Heart?
Very few cases of side effects of Azadine on the heart have been reported.
Azadine 150mg Injection should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
If you are suffering from any of the following diseases, you should not take Azadine 150mg Injection unless your doctor advises you to do so -
Is this Azadine 150mg Injection habit forming or addictive?
Azadine 150mg Injection does not cause addiction.
Is it safe to drive or operate heavy machinery when consuming?
After taking Azadine 150mg Injection you may feel sleepy. So it is not advised to perform these activities.
Is it safe?
Yes, but take Azadine 150mg Injection only as per medical advice.
Is it able to treat mental disorders?
There is no benefit of taking Azadine 150mg Injection for mental disorders.
Interaction between Food and Azadine 150mg Injection
Due to a lack of research, nothing can be said about the consequences of taking Azadine 150mg Injection together with food.
Interaction between Alcohol and Azadine 150mg Injection
Information about the interaction of Azadine 150mg Injection and alcohol is not currently available because this topic has not been researched yet.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Vidaza (azacitidine)
Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Celazadine® (azacitidine)