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Azafab is an antineoplastic agent that works as a hypomethylating agent. It is primarily used in the treatment of certain types of myelodysplastic syndromes (MDS), a group of bone marrow disorders. Azafab helps restore normal gene function, promoting healthy blood cell production and inhibiting the growth of abnormal cells in the bone marrow.
Azafab incorporates into DNA and RNA, inhibiting DNA methyltransferase. This results in hypomethylation of DNA and reactivation of silenced tumor suppressor genes. The drug also disrupts RNA processing, which may contribute to its anti-cancer effects. These mechanisms slow or stop the growth of abnormal cells and promote normal cell development.
Azafab is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
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Geriatric |
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Is the use of Azafab safe for pregnant women?
Azafab shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.
Is the use of Azafab safe during breastfeeding?
Taking Azafab may lead to serious side effects if you are breastfeeding. Azafab should not be taken by breastfeeding women unless prescribed by the doctor.
What is the effect of Azafab on the Kidneys?
Azafab rarely harms the kidneys.
What is the effect of Azafab on the Liver?
Very few cases of side effects of Azafab on the liver have been reported.
What is the effect of Azafab on the Heart?
Azafab is rarely harmful for the heart.
Azafab should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
If you are suffering from any of the following diseases, you should not take Azafab unless your doctor advises you to do so -
Is this Azafab habit forming or addictive?
Forming a habit of Azafab has not been reported.
Is it safe to drive or operate heavy machinery when consuming?
No, you should do not do anything that requires concentration and attention as the Azafab can make you feel drowsy.
Is it safe?
Azafab is safe but it is important to consult a doctor before taking it.
Is it able to treat mental disorders?
No, the use of Azafab in mental disorders is not effective.
Interaction between Food and Azafab
Due to a lack of research, nothing can be said about the consequences of taking Azafab together with food.
Interaction between Alcohol and Azafab
Due to lack of research, there is no information about the side effects of taking Azafab with alcohol.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Vidaza (azacitidine)
Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Celazadine® (azacitidine)