Azatend 100mg Injection

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1 Injection in 1 Vial Out of Stock
₹ 7600
1 Injection 1 Vial ₹ 7600
  • Out of Stock

  • Manufactured by: Zydus Cadila
  • Contains / Salt: Azacitidine

Azatend 100mg Injection

1 Injection in 1 Vial
₹ 7600
1 Injection | 1 Vial
₹ 7600
people have bought this recently
Free shipping all over India
  • Manufactured by: Zydus Cadila
  • Contains / Salt: Azacitidine

Azatend Information

Azatend is an antineoplastic agent that works as a hypomethylating agent. It is primarily used in the treatment of certain types of myelodysplastic syndromes (MDS), a group of bone marrow disorders. Azatend helps restore normal gene function, promoting healthy blood cell production and inhibiting the growth of abnormal cells in the bone marrow.

Indications:

  1. Myelodysplastic Syndromes (MDS):
    • Refractory anemia or anemia with excess blasts.
    • Chronic myelomonocytic leukemia (CMML).
    • Intermediate-2 and high-risk MDS based on the International Prognostic Scoring System (IPSS).
  2. Acute Myeloid Leukemia (AML):
    • For patients with AML who are not candidates for intensive chemotherapy.

Azatend incorporates into DNA and RNA, inhibiting DNA methyltransferase. This results in hypomethylation of DNA and reactivation of silenced tumor suppressor genes. The drug also disrupts RNA processing, which may contribute to its anti-cancer effects. These mechanisms slow or stop the growth of abnormal cells and promote normal cell development.



Azatend Benefits & Uses

Azatend is used to treat the following -

Main Benefits

Other Benefits

Azatend Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Myelodysplastic Syndrome
  • Before or After Meal: Either
  • Single Maximum Dose: 125 mg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Myelodysplastic Syndrome
  • Before or After Meal: Either
  • Single Maximum Dose: 125 mg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor

Azatend Related Warnings

  • Is the use of Azatend safe for pregnant women?


    Azatend should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.

    Severe
  • Is the use of Azatend safe during breastfeeding?


    Women who are breastfeeding may experience severe harmful effects after taking Azatend. It should only be taken after medical advice.

    Severe
  • What is the effect of Azatend on the Kidneys?


    Very few cases of side effects of Azatend on kidney have been reported.

    Mild
  • What is the effect of Azatend on the Liver?


    Side effects of Azatend rarely affect the liver.

    Mild
  • What is the effect of Azatend on the Heart?


    Very few cases of side effects of Azatend on the heart have been reported.

    Mild


Severe Interaction of Azatend with Other Drugs

Azatend should not be taken with following medicines due to severe side effects it may cause to patients -

Severe



Azatend Contraindications

If you are suffering from any of the following diseases, you should not take Azatend unless your doctor advises you to do so -



Frequently asked Questions about Azatend

  • Is this Azatend habit forming or addictive?


    Azatend is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should do not do anything that requires concentration and attention as the Azatend can make you feel drowsy.

    Dangerous
  • Is it safe?


    Azatend should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Azatend cannot treat any kind of mental disorder.

    No

Azatend Interactions with Food and Alcohol

  • Interaction between Food and Azatend


    There is no information on the effects of taking Azatend with food, because this topic has not been scientifically researched yet.

    Unknown
  • Interaction between Alcohol and Azatend


    Due to lack of research, there is no information about the side effects of taking Azatend with alcohol.

    Unknown


See all substitutes for Azatend


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Vidaza (azacitidine)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Celazadine® (azacitidine)



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