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Azatend is an antineoplastic agent that works as a hypomethylating agent. It is primarily used in the treatment of certain types of myelodysplastic syndromes (MDS), a group of bone marrow disorders. Azatend helps restore normal gene function, promoting healthy blood cell production and inhibiting the growth of abnormal cells in the bone marrow.
Azatend incorporates into DNA and RNA, inhibiting DNA methyltransferase. This results in hypomethylation of DNA and reactivation of silenced tumor suppressor genes. The drug also disrupts RNA processing, which may contribute to its anti-cancer effects. These mechanisms slow or stop the growth of abnormal cells and promote normal cell development.
Azatend is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
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Geriatric |
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Is the use of Azatend safe for pregnant women?
Azatend should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.
Is the use of Azatend safe during breastfeeding?
Women who are breastfeeding may experience severe harmful effects after taking Azatend. It should only be taken after medical advice.
What is the effect of Azatend on the Kidneys?
Very few cases of side effects of Azatend on kidney have been reported.
What is the effect of Azatend on the Liver?
Side effects of Azatend rarely affect the liver.
What is the effect of Azatend on the Heart?
Very few cases of side effects of Azatend on the heart have been reported.
Azatend should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
If you are suffering from any of the following diseases, you should not take Azatend unless your doctor advises you to do so -
Is this Azatend habit forming or addictive?
Azatend is not addictive in nature.
Is it safe to drive or operate heavy machinery when consuming?
No, you should do not do anything that requires concentration and attention as the Azatend can make you feel drowsy.
Is it safe?
Azatend should be used only after doctor's advice.
Is it able to treat mental disorders?
No, Azatend cannot treat any kind of mental disorder.
Interaction between Food and Azatend
There is no information on the effects of taking Azatend with food, because this topic has not been scientifically researched yet.
Interaction between Alcohol and Azatend
Due to lack of research, there is no information about the side effects of taking Azatend with alcohol.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Vidaza (azacitidine)
Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Celazadine® (azacitidine)