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Azaplast is an antineoplastic agent that works as a hypomethylating agent. It is primarily used in the treatment of certain types of myelodysplastic syndromes (MDS), a group of bone marrow disorders. Azaplast helps restore normal gene function, promoting healthy blood cell production and inhibiting the growth of abnormal cells in the bone marrow.
Azaplast incorporates into DNA and RNA, inhibiting DNA methyltransferase. This results in hypomethylation of DNA and reactivation of silenced tumor suppressor genes. The drug also disrupts RNA processing, which may contribute to its anti-cancer effects. These mechanisms slow or stop the growth of abnormal cells and promote normal cell development.
Azaplast is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
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Geriatric |
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Is the use of Azaplast safe for pregnant women?
Azaplast should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.
Is the use of Azaplast safe during breastfeeding?
Taking Azaplast may lead to serious side effects if you are breastfeeding. Azaplast should not be taken by breastfeeding women unless prescribed by the doctor.
What is the effect of Azaplast on the Kidneys?
Azaplast may have mild side effects on the kidneys.
What is the effect of Azaplast on the Liver?
Azaplast is rarely harmful for the liver.
What is the effect of Azaplast on the Heart?
Azaplast may have mild side effects on the heart. Most people will never see any effect on the heart.
Azaplast should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
If you are suffering from any of the following diseases, you should not take Azaplast unless your doctor advises you to do so -
Is this Azaplast habit forming or addictive?
No, there is no any evidence that Azaplast is addictive.
Is it safe to drive or operate heavy machinery when consuming?
No, you should not drive or operate heavy machinery after taking Azaplast as you may feel sleepy.
Is it safe?
Azaplast is safe but it is important to consult a doctor before taking it.
Is it able to treat mental disorders?
No, Azaplast cannot treat any kind of mental disorder.
Interaction between Food and Azaplast
There is no information on the effects of taking Azaplast with food, because this topic has not been scientifically researched yet.
Interaction between Alcohol and Azaplast
Due to lack of research, there is no information about the side effects of taking Azaplast with alcohol.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Vidaza (azacitidine)
Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Celazadine® (azacitidine)