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Divigel is a prescription drug, available for use as Gel. It is typically used for the treatment of Post Menopausal Osteoporosis, Urethritis, Vaginal atrophy. The alternative uses of Divigel have also been explained below.
The optimal dosage of Divigel is largely dependent on the individual's body weight, medical history, gender and age. Individual symptoms and route of administration also determines the right dosage. This information has been provided in detail in the dosage section.
Common side effects of Divigel include Weight gain, Metrorrhagia, Edema. Apart from the aforementioned side effects, Divigel can also lead to other problems, which have been listed below. Such side effects of Divigel normally do not last long and go away once the treatment is completed. If, however, they worsen or do not go away, please speak with your physician.
Divigel's effect during pregnancy is Severe and Severe while nursing. Further, the section on Divigel related warnings talks about Divigel's effects on the liver, heart and kidney.
Divigel can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Divigel in conditions like High Blood Pressure, Blood Clotting Disorders, Thrombophlebitis. The section on Divigel contraindications lists all such conditions.
Drug interactions for Divigel have been reported in the medical literature. See below for a complete list.
In addition to the above precautions for Divigel, it is important to know that it is safe while driving, and is habit-forming.
Divigel is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult(Female) |
|
Geriatric |
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Is the use of Divigel safe for pregnant women?
Pregnant women may get severe side effects after taking Divigel. If you are pregnant, do not take Divigel without a doctor's advice.
Is the use of Divigel safe during breastfeeding?
Divigel should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.
What is the effect of Divigel on the Kidneys?
There may be some adverse effects on kidney after taking Divigel. If you observe any such side effects, stop taking this drug. Consume this medicine again only if your doctor advises you to do so.
What is the effect of Divigel on the Liver?
Divigel is rarely harmful for the liver.
What is the effect of Divigel on the Heart?
Divigel can have moderate side effects on the heart. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.
Divigel should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Divigel unless your doctor advises you to do so -
Is this Divigel habit forming or addictive?
Divigel does not cause addiction.
Is it safe to drive or operate heavy machinery when consuming?
Divigel will not make you feel sleepy or drowsy. So you drive or operate machinery safely.
Is it safe?
Yes, Divigel is safe but you must consult your doctor before taking it.
Is it able to treat mental disorders?
No, Divigel is not used to treat mental disorders.
Interaction between Food and Divigel
There isn't any research available on the side effects of taking Divigel with food.
Interaction between Alcohol and Divigel
Due to lack of research, there is no information about the side effects of taking Divigel with alcohol.
No, Divigel should not be discontinued without doctors advice. You are recommended to always consult a doctor before discontinuing this medicine.
Long-term use of Divigel at higher doses increases the risk of endometrial cancer in postmenopausal women. It depends on the duration of treatment and doses of this drug. If you are taking this drug for prolonged duration and having recurring abnormal vaginal bleeding then consult it with your doctor without further delay.
Yes, Divigel may cause spotting or intermenstrual bleeding, it has been associated with spotting but it occurs in a few cases only. It is a rare side effect of this drug. This might occur due to hormonal imbalance.
Yes Divigel can be taken along with levothyroxine at the same time. Levothyroxine does not appear to interfere with the efficacy of Divigel. Hence, it is alright to take them together. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.
Divigel is a brand name of estradiol and it comes in the form of a tablet (solid unit dosage form). It belongs to the class of drug known as estrogen. Divigel is a prescription drug which is used for hormone replacement therapy in menopausal women. It is also used for the prevention of postmenopausal osteoporosis.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Estrace (estradiol)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 306-309
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 526-528